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Metabolic Stability More consistent drug levels could provide: Steady appetite suppression: Avoiding the "feast-famine" cycle of weekly dosing Consistent energy levels: Reduced fluctuation in metabolic rate Better glucose control: Continuous incretin effect rather than peaks and valleys Improved sleep: Less variation in nocturnal glucose and hunger hormones 3

Metabolic Effects Beyond Weight Loss Both medication types improve metabolic markers, but dual agonists might offer some advantages in certain areas

Tirzepatide (Mounjaro), a dual GIP/GLP-1 receptor agonist, has received MHRA marketing authorisation

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